Where Our Name
Makes The Difference

Grace Internal Medicine

Dedicated to delivering quality medical care across the upstate of South Carolina for over a decade, Dr. Leon Buffaloe and the team at Grace Internal Medicine are here to help patients receive comprehensive treatment.

Should you take the COVID-19 Vaccination?


Our Care Philosophy

As internists, the team at Grace Internal Medicine is dedicated to treating all of our patients with the utmost dignity and respect. We are passionate about understanding your needs, and your goals at all times.

You will play an active role in your treatment and your voice heard when you have questions or concerns.

Our Featured Services

Chronic Disease Management

We treat a variety of chronic diseases such as hypertension, heart disease, asthma, Alzheimer’s and arthritis.


We have a special focus on treating patients with diabetes with a comprehensive approach.

Weight Loss Management

Losing weight can be difficult. Our team can help you reach your fitness goals. Call our office for a consultation today.


Our office will ensure that you are up to date on all of your age-appropriate cancer screenings and routine immunization.

Our Vision

Welcome To Our Office

At Grace Internal Medicine, where our name makes a difference, our vision is to provide a welcoming atmosphere of feeling through the latest treatment options and technology.

Dr. Leon Buffaloe

Meet Dr. Leon Buffaloe Jr.


Dr. Leon Buffaloe Jr. is an internist in Simpsonville, SC. Dr. Buffaloe is dedicated to the prevention, diagnosis, treatment, and management of diseases that affect his patients. As an internist, Dr. Buffaloe’s goal is to ensure that his patients are getting comprehensive care that transcends a specific symptom or health condition. 

0 +
Years Of Service
0 +
Lives Changed
0 %
0 +
Online Reviews

Experienced & Trustworthy

Your Comfort Matters.

What Sets Us Apart?

We are committed to providing family care that is both high quality and affordable. For any questions, please call our office.

We believe that patient education extends past treatment. Our goal is to provide a personalized experience with all of our patients. We look forward to welcoming you!

With over 10+ years of experience, our office is equipped with the latest state-of-the-art equipment. We are also currently offering Telehealth appointments to help our patients are stay safe.

Contact Us Today

What Our Patients Say


Thank you for your help as we work to keep our patients and team safe and healthy!

Office Hours: Monday to Friday: 8:00 am – 5:00 pm

* We are closed on all major holidays.

Telemedicine: We are currently accepting patients via telehealth. You can also request an appointment via MyChart.

Masks: Masks are required to enter our building.

Annual Check-ups & Follow-ups: We are reserving our building for well care only. Please call us before entering if you have sick symptoms.

Sick Visits: Any patient with sick symptoms (fever, cough, sore throat, etc.) will be seen via a scheduled telehealth appointment. Please call our office for more information.

Questions: Please call our office at 864-757-5177. We are located at 114 B Hospital Drive, Simpsonville, SC 29681.

Las Pacientes Hispanos Son Bienvenidas!

Nuestras puertas de oficina abren en enero de 2021

Como internistas, el equipo de Grace Internal Medicine se dedica a tratar a todos nuestros pacientes con la mayor dignidad y respeto. Nos apasiona comprender sus necesidades y sus objetivos en todo momento.

Usted desempeñará un papel activo en su tratamiento y su voz se escuchará cuando tenga preguntas o inquietudes.