Dr. Leon Buffaloe, Jr. was born in Washington, DC, and raised in Prince George’s County, Maryland. At 18, he left home to serve his country as an Army Combat Medic. During his 12 years of active duty, Dr. Buffaloe served in Operation Desert Storm, Operation Restore Hope, and the Iraq War. Following his tour in Somalia, he was accepted into the Army’s Licensed Practical Nurse Program, where he continued to expand his expertise across multiple areas of nursing.
Dr. Buffaloe graduated with Cum Laude honors in Biological Studies from the University of South Carolina in 2004 and went on to earn his degree from the University’s School of Medicine in 2008.
After completing his residency at Palmetto Health Richland (now Prisma Health Richland), he practiced as a physician with SELF Regional in Laurens, SC, before moving to Simpsonville to help open a clinic for PRISMA Health Upstate. Guided by more than 30 years of comprehensive healthcare experience, Dr. Buffaloe founded Grace Internal Medicine to establish a dedicated, independent practice focused on exceptional patient care.
With a welcoming, comfortable, and approachable environment, Grace Internal Medicine proudly serves community members from all over the Upstate. Whether you are a longtime patient, a new face to the practice, or a member of our staff, Dr. Buffaloe and his team are fully committed to making a positive difference in your healthcare journey.
Outside the Clinic
Dr. Buffaloe met his wife, Asante—an Army surgical technologist who is now a Family Medicine Physician—while on tour in Honduras in 1999. Together, they have four children (Dominique, Nicholas, Leon III, and Naomi) and a beloved beagle named CJ. In his downtime, Dr. Buffaloe enjoys spending quality time with his family and staying actively involved in his church community.
